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Showing 1 to 12 of 22 entries
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[Key factors in design of case report form].

Yao xue xue bao = Acta pharmaceutica Sinica

Fu HJ, Luo XX.
PMID: 26911041
Yao Xue Xue Bao. 2015 Nov;50(11):1452-5.

Case report form (CRF) is a key document for data collection in clinical trials. A well-designed CRF is required for database construction, data accuracy, data query/cleaning, CRF completion and statistical analysis. A well-defined process or SOP should be in...

[Data quality in clinical trials: the role of blind review].

Yao xue xue bao = Acta pharmaceutica Sinica

Yu YP, Yao C.
PMID: 26911051
Yao Xue Xue Bao. 2015 Nov;50(11):1498-501.

Blind review is one of the most important milestones in clinical trials, which connects data management process to statistical analysis. During blind review, data quality should be reviewed and assessed on both data management and statistical aspects. The primary...

[Chemical constituents of Ligularia duciformis].

Yao xue xue bao = Acta pharmaceutica Sinica

Fu KZ, Yu NJ, Zhang Y, Zhao YM.
PMID: 17702399
Yao Xue Xue Bao. 2007 Jun;42(6):621-4.

Ligularia duciformis is a plant of the Ligularia genus (Compositae) which has been reported to have therapeutic effects of treating diseases such as bronchitis and coughing. In order to find out the bioactive components, the 85% ethanol extract of...

[Advances in pharmacological studies of Panax notoginseng saponins on brain ischemia-reperfusion injury].

Yao xue xue bao = Acta pharmaceutica Sinica

Yang PF, Song XY, Chen NH.
PMID: 29896951
Yao Xue Xue Bao. 2016 Jul;51(7):1039-46.

Sanqi in Chinese herbal medicine is the root and rhizoma of Panax notoginseng (Burk.) F.H. Chen, which belongs to genus Panax in the Araliaceae family and is widely used as a tonic medicine in the traditional Chinese medicine. The...

[Concise analysis for innovation of pioneering and follow-on drugs].

Yao xue xue bao = Acta pharmaceutica Sinica

Guo ZR.
PMID: 29897709
Yao Xue Xue Bao. 2016 Aug;51(8):1179-84.

More attention has been paid to the pioneering drug innovation since the new millennium, while the creation space of fast-followed drugs is shrinking due to the serious risks observed in the clinical phases following marketing. Innovative drug discovery aiming...

Challenges in Drug Discovery for Thiazolidinedione Substitute.

Yao xue xue bao = Acta pharmaceutica Sinica

Ye J.
PMID: 22427718
Yao Xue Xue Bao. 2011 Oct 01;1(3):137-142. doi: 10.1016/j.apsb.2011.06.011.

Thiazolidinedione (TZD) is a powerful insulin sensitizer in the treatment of type 2 diabetes. It acts as a ligand to the nuclear receptor PPARĪ³ (peroxisome proliferator-activated receptor-gamma) and induces transcription of PPARĪ³ responsive genes. TZD controls lipid synthesis and...

[PROGRESS ON PENICILLIN ANTIBIOTICS].

Yao xue xue bao = Acta pharmaceutica Sinica

CHEN W.
PMID: 14075917
Yao Xue Xue Bao. 1962 Jul;9:439-52.

No abstract available.

[The application of enzyme-sensitive activatable cell-penetrating peptides to targeted delivery system].

Yao xue xue bao = Acta pharmaceutica Sinica

He F, Cao L, Zhang XJ, Xiang B, Cao DY, Qi XR.
PMID: 25975019
Yao Xue Xue Bao. 2015 Feb;50(2):141-7.

Cell-penetrating peptides (CPPs) offer a non-selective and receptor-independent mode to promote cellular uptake. Although the non-specificity of CPP-mediated internalization allows this approach applicable to a wide range of tumor types potentially, their universality is a significant obstacle to their...

[Process and method for CDISC-based CRF annotation].

Yao xue xue bao = Acta pharmaceutica Sinica

Wang HW, Deng YZ, Liu D.
PMID: 26911046
Yao Xue Xue Bao. 2015 Nov;50(11):1474-9.

A CDASH-based CRF annotation plays an important role in database setup and data verification. The STDM-based CRF annotation is also one of the essential documents when the package of clinical trial data is submitted to the regulatory authority. This...

[Master documentation and records in the clinical data management].

Yao xue xue bao = Acta pharmaceutica Sinica

Sun HL, Xu G, Li W, Wei ZH, Ding L.
PMID: 26911025
Yao Xue Xue Bao. 2015 Nov;50(11):1365-6.

This list of clincal data management documentation is to ensure standardized and adequate archival of trial documents and records in clinical data management, which is applicable to all of phase I-IV clinical trials.

[Computational chemistry in structure-based drug design].

Yao xue xue bao = Acta pharmaceutica Sinica

Cao R, Li W, Sun HZ, Zhou Y, Huang N.
PMID: 24133970
Yao Xue Xue Bao. 2013 Jul;48(7):1041-52.

Today, the understanding of the sequence and structure of biologically relevant targets is growing rapidly and researchers from many disciplines, physics and computational science in particular, are making significant contributions to modern biology and drug discovery. However, it remains...

[Announcement of retraction].

Yao xue xue bao = Acta pharmaceutica Sinica

[No authors listed]
PMID: 19306522
Yao Xue Xue Bao. 2008 Mar;43(3):322.

No abstract available.

Showing 1 to 12 of 22 entries